富维斯特朗
帕博西利布
医学
危险系数
内科学
肿瘤科
安慰剂
乳腺癌
转移性乳腺癌
芳香化酶抑制剂
癌症
妇科
置信区间
雌激素受体
三苯氧胺
病理
替代医学
作者
Nicholas C. Turner,Dennis J. Slamon,Jungsil Ro,Igor Bondarenko,Seock‐Ah Im,Norikazu Masuda,Marco Colleoni,Angela DeMichele,Sherene Loi,Sunil Verma,Hiroji Iwata,Nadia Harbeck,Sibylle Loibl,Fabrice André,Kathy Puyana Theall,Xin Huang,C. Giorgetti,Cynthia Huang Bartlett,Massimo Cristofanilli
标识
DOI:10.1056/nejmoa1810527
摘要
Among patients with hormone-receptor-positive, HER2-negative advanced breast cancer who had sensitivity to previous endocrine therapy, treatment with palbociclib-fulvestrant resulted in longer overall survival than treatment with placebo-fulvestrant. The differences in overall survival in the entire trial group were not significant. (Funded by Pfizer; PALOMA-3 ClinicalTrials.gov number, NCT01942135 .).
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