化学
区域选择性
级联
组合化学
级联反应
有机化学
立体化学
催化作用
色谱法
作者
Tianzi Dai,Cui Chen,Xueyu Qi,Yanshu Cheng,Qian He,Xiaofei Zhang,Xiaomin Luo,Chunhao Yang
摘要
A facile and efficient strategy to synthesize substituted thiazoles via a cascade reaction from chromone derivatives and thioamides in an environmentally benign medium was developed. This cascade reaction involves a Michael addition/intramolecular cyclization process and a broad scope of reversed regioselectivity products was prepared in a short reaction time with excellent yields. The reversed regioselectivity was also explained by DFT calculations.
科研通智能强力驱动
Strongly Powered by AbleSci AI