医学
自身抗体
免疫学
肺结核
免疫缺陷
细胞因子
淋巴细胞
结核分枝杆菌
内科学
抗体
病理
免疫系统
作者
Sarah Browne,Peter D. Burbelo,Ploenchan Chetchotisakd,Yupin Suputtamongkol,Sasisopin Kiertiburanakul,Pamela A. Shaw,Jennifer L. Kirk,Kamonwan Jutivorakool,Rifat Zaman,Li Ding,Amy P. Hsu,Smita Y. Patel,Kenneth N. Olivier,Viraphong Lulitanond,Piroon Mootsikapun,Siriluck Anunnatsiri,Nasikarn Angkasekwinai,Boonmee Sathapatayavongs,Po‐Ren Hsueh,Chi-Chang Shieh
标识
DOI:10.1056/nejmoa1111160
摘要
Neutralizing anti-interferon-γ autoantibodies were detected in 88% of Asian adults with multiple opportunistic infections and were associated with an adult-onset immunodeficiency akin to that of advanced HIV infection. (Funded by the National Institute of Allergy and Infectious Diseases and the National Institute of Dental and Craniofacial Research; ClinicalTrials.gov number, NCT00814827.).
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