100% atom-economical and highly regio- and stereoselective iodosulfenylation of alkynes: a reagentless and sustainable approach to access (E)-β-iodoalkenyl sulfides and (Z)-tamoxifen

A 100% atom-economical iodosulfenylation of alkynes is developed using only iodine and disulfides via the in situ formation of the corresponding sulfenyl iodide intermediates to access ( E )-β-iodoalkenyl sulfides and ( Z )-tamoxifen.