Social pain sharing boosts interpersonal brain synchronization in female cooperation

Social pain sharing promotes cooperation, but we still don't know its neural basis. The present study employed functional near-infrared spectroscopy (fNIRS)-based hyperscanning technology to investigate whether interpersonal brain synchronization (IBS) increased between females engaging in cooperative activities after a shared experience of social pain. We utilized the Cyberball paradigm, manipulating social pain by regulating the number of catches for the participants. Dyads in the shared social pain (SP) group received passes only at the beginning of the game, whereas dyads in the control (CT) group had the same number of catches as other players. The results indicate that participants in the SP group showed significant IBS in the right superior frontal cortex (r-SFC, p < 0.05) and left middle frontal cortex (l-MFC, p < 0.05), but no channels in the CT group showed significant IBS (p > 0.05). Further analysis revealed that IBS in r-SFC was significantly higher in the SP group compared to the CT group (p < 0.05). Additionally, IBS in r-SFC was positively correlated with the level of cooperation (r = 0.66, p < 0.001). This study elucidates the neural basis of enhanced cooperation facilitated by shared social pain at the interbrain level. However, it is crucial to acknowledge that this study exclusively enrolled female participants. The generalizability of these findings across genders is yet to be confirmed.