化学
卡宾
二氟卡宾
蒂奥-
试剂
氟
甲醇
反应性(心理学)
药物化学
烯烃
路易斯酸
锂(药物)
光化学
有机化学
甲醇
催化作用
替代医学
病理
内分泌学
医学
作者
Egor A. Ilin,Vladimir O. Smirnov,Alexander D. Dilman
标识
DOI:10.1016/j.jfluchem.2022.110025
摘要
Generation of carbenes bearing a fluorine atom and an arylthio group from the difluorinated silicon reagents is described. The carbene generation is performed using a combination of lithium methoxide and lithium chloride, which behave as Lewis basic and Lewis acidic activators, respectively. The reactivity of fluoro(thio)carbenes was evaluated by trapping with an alkene and an aminoborane. Quantum chemical calculations allowed comparison of the fluoro(thio)carbene with difluorocarbene.
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