Objective:To investigate the correlation among serum triglyceride concentration, plasma factorⅦ clouting(FⅦc), tPA, PAI I activity in 73 cases with Coronary heart disease(CHD).Methods:153 Cases Were divided into four groups:73 patients with CHD were divided into two groups based on serum triglyceride concertration. 40 subjects have high triglyceride without CHD; another 40 subjects with normal triglyceride. The results in 73 patients with CHD and 40 Subjects With High triglyceride were compared with that in 40 normal triglyceride. Serum triglyceride was measured by enzyme method, The plasma PAI0 I, tPA activity by spectorphotometry, the plasma FⅦc by onestage method.Results:FⅦc and PAI I activity in patients with CHD and in serum high triglyceride group were higher than in those with normal triglyceride group. FⅦc and PAI I activity in high triglyceride patients with CHD were significantly higher than in those high triglyceride cases without CHD.Conclusion:Serum high triglyceride concentuition is associatied with FⅦc, tPA and PAI 1.