The soluble fms-like tyrosine kinase (sFlt-1)/placental growth factor (PlGF) ratio seems to predict early-onset-preeclampsia (PE) and severe PE accurately. We tested if changes of sFlt-1, PIGF and sFlt-1/PIGF ratio directly before and after delivery are able to identify women at risk of complicated puerperal course in women delivering above 34 weeks of gestation.