The number of tourists visiting high altitude areas has increased in recent years, and they face the threat of acute mountain sickness (AMS). The reported prevalence of AMS varies between 15% and 80% depending on the speed of ascent, absolute altitude reached, and individual susceptibility.1–3 We had a chance to evaluate the incidence of AMS among passengers who were first exposed to high altitude by taking the Tibetan railway train. A summary is presented here.