多囊卵巢
高雄激素血症
医学
胰岛素抵抗
无排卵
代谢综合征
肥胖
2型糖尿病
超重
糖尿病
内科学
内分泌学
生物信息学
生物
作者
Mar Lorenzo,Nunzia Cacciapuoti,Maria Serena Lonardo,Gilda Nasti,Claudia Gautiero,A. Belfiore,Bruna Guida,Martina Chiurazzi
标识
DOI:10.1007/s13668-023-00479-8
摘要
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder in women of reproductive age worldwide. This disease causes menstrual, metabolic, and biochemical abnormalities such as hyperandrogenism, oligo-anovulatory menstrual cycles, polycystic ovary, hyperleptinemia, insulin resistance (IR), and cardiometabolic disorders, often associated with overweight or obesity and visceral adiposity.The etiology and pathophysiology of PCOS are not yet fully understood, but insulin seems to play a key role in this disease. PCOS shares an inflammatory state with other chronic diseases such as obesity, type II diabetes, and cardiovascular diseases; however, recent studies have shown that a healthy nutritional approach can improve IR and metabolic and reproductive functions, representing a valid therapeutic strategy to ameliorate PCOS symptomatology. This review aimed to summarize and collect evidence about different nutritional approaches such as the Mediterranean diet (MedDiet) and the ketogenic diet (KD), as well as bariatric surgery and nutraceutical supplementation as probiotics, prebiotics, and synbiotics, among the others, used in patients with PCOS.
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