MISEV2023: Shaping the Future of EV Research by Enhancing Rigour, Reproducibility and Transparency

Extracellular vesicles (EVs) are an area of growing interest due to their strong potential as biomarkers and therapeutics. Defined as lipid bilayer membrane-delimited particles, which are non-replicative and nano- to micro-sized, EVs are released by all cell types in every organism and have diverse roles in both normal physiology and disease. Despite the challenges associated with the study of EVs, the number of EV-related publications has been growing every year, necessitating the standardisation and proper reporting of the methodologies used for their study. In line with this, the International Society of Extracellular Vesicles (ISEV) published the Minimal Information for Studies of Extracellular Vesicles in 2014 (MISEV2014) [ 1 ], and later, an updated version in 2018 (MISEV2018) in an attempt to improve rigour and standardisation in EV studies across different groups [ 2 ].