丹参
DPPH
化学
抗氧化剂
圆二色性
维生素C
鼠尾草
维生素E
衍生工具(金融)
立体化学
传统医学
色谱法
有机化学
生物化学
中医药
替代医学
医学
经济
病理
金融经济学
作者
Jianming Xue,Jun Chen,Feng Qi,Hong Wu,Zhimin Wang,Liping Dai
标识
DOI:10.1080/14786419.2023.2198710
摘要
A new salvianolic acid derivative, (7′E)-(7S, 8S)-salvianolic acid V (1), together with four previously described compounds (2-5) were obtained from the n-butanol fraction of Salvia miltiorrhiza flowers. Their structures were established by a series of spectroscopic methods, and the absolute configuration of 1 was determined by electronic circular dichroism (ECD) calculation. Salvianolic acids (1) and phenolic acids (2-4) showed stronger DPPH free radical scavenging abilities and certain protective effects against H2O2-induced human skin fibroblast (HSF) cells oxidative damage, in which compound 1 (IC50 7.12 μM) possessed more noticeable free radical scavenging activity than the positive control vitamin C (IC50 14.98 μM).
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