转移
癌症研究
生物
癌细胞
癌症
旁分泌信号
受体
生物化学
遗传学
作者
Chun-Miao Deng,Guo-Geng Zhang,Qin‐Wen Liu,Jiao-Jiao Xu,Zhichao Liu,Jing Yang,Tao‐Yang Xu,Zhigang Li,Fan Zhang,Bin Li
出处
期刊：Cancer Research
[American Association for Cancer Research]
日期：2023-03-13
卷期号：83 (11): 1851-1865
被引量：32
标识
DOI：10.1158/0008-5472.can-22-3490
摘要
Metastatic cancer cells upregulate ANO1 to activate cell-intrinsic and -extrinsic mechanisms that alter cholesterol metabolism and stimulate fibroblasts, which can be targeted with ANO1 inhibitors to inhibit metastatic growth. See related commentary by Singh and Mehla, p. 1759.
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