脑淀粉样血管病
医学
生物标志物
淀粉样蛋白(真菌学)
病理
神经科学
痴呆
心理学
疾病
化学
生物化学
作者
Ty Shang,Peter V. Sguigna,Marco C. Pinho,William Moore,Erica Jones,Suriya Subramanian,Parth Upadhyaya,Brendan Kelley,Kimmo J. Hatanpaa,Jack Raisanen
出处
期刊:Neurology
[Lippincott Williams & Wilkins]
日期:2025-01-02
卷期号:104 (2)
被引量:1
标识
DOI:10.1212/wnl.0000000000210258
摘要
Cerebral microbleeds (cMBs) are common imaging findings in conditions related to cerebral amyloid angiopathy (CAA). Blood-brain barrier (BBB) leakage is considered pivotal in their pathogenesis. This study investigates the potential role of cerebral microenhancement (cME) as an imaging biomarker on 3D T1 black-blood MRI (BB-MRI) for BBB rupture, predicting the formation of cMBs in inflammatory CAA variants.
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