Rational design of flexible microneedles coupled with CaO 2 @PDA-loaded nanofiber films for skin wound healing on diabetic rats

@PDA nanoparticles demonstrated a high level of CD31 and low level of TNF-α, leading to accelerated diabetic skin-wound closure. These distinctive features demonstrate that our microneedle system can be a facile candidate for efficient wound healing in patients with diabetes and may be applied in various biomedical fields.