医学
口腔微生物群
慢性阻塞性肺病
肺
微生物群
肺炎
肺病
失调
疾病
哮喘
重症监护医学
呼吸道疾病
免疫学
内科学
牙科
口腔健康
病理
生物信息学
生物
作者
Nathaniel Gaeckle,Alexa A. Pragman,Kathryn M. Pendleton,Arianne K. Baldomero,Gerard J. Criner
出处
期刊:Respiratory Care
[American Association for Respiratory Care]
日期:2020-03-10
卷期号:65 (8): 1211-1220
被引量:73
标识
DOI:10.4187/respcare.07332
摘要
Poor oral health has long been recognized as a clinical risk factor for developing lung infections. Recent data using culture-independent techniques assessing the microbiome in healthy subjects have demonstrated that chronic microaspiration establishes a very similar microbial community between the mouth and lung, suggesting these 2 anatomic regions are closely intertwined. Dental disease is driven and aided by a dysbiosis in the oral microbiome, and evidence is mounting that implicates the microbiome in a variety of lung diseases including asthma, COPD, pulmonary fibrosis, and pneumonia. This review describes common dental conditions and potential mechanisms by which poor oral health may contribute to lung disease. We also review the current literature drawing associations between poor oral health and lung disease
科研通智能强力驱动
Strongly Powered by AbleSci AI