Noninvasive Carbon Dioxide Monitoring During Neurosurgical Procedures in Adults: End-Tidal Versus Transcutaneous Techniques

We prospectively compared transcutaneous (TC) versus end-tidal (ET) carbon dioxide monitoring during neurosurgical procedures in adults.After calibration and an equilibration time for the TC-CO2 monitor, arterial blood gas (ABG) values were obtained as clinically indicated. The PaCO2 values were compared with the values recorded by the noninvasive monitors (TC and ET).The ET-CO2 to PaCO2 difference was 6.1 +/- 5.6 mm Hg, and the TC-CO2 to PaCO2 difference was 3.7 +/- 2.9 mm Hg. The difference between the PaCO2 and ET-CO2 was 3 mm Hg or less in 17 of 57 values, while the difference between the PaCO2 and TC-CO2 was 3 mm Hg or less in 35 of 57 values. Linear regression analysis of ET-CO2 versus PaCO2 revealed a slope of 0.381 +/- 0.007. Linear regression analysis of TC-CO2 versus PaCO2 revealed a slope of 1.17 +/- 0.008.Transcutaneous CO2 monitoring provides a more accurate estimate of PaCO2 than ET-CO2 monitoring during neurosurgical procedures.