Enantioselective synthesis of 2,3-disubstituted trans-2,3-dihydrobenzofurans using a Brønsted base/thiourea bifunctional catalyst

The enantioselective synthesis of 2,3-disubstitutedtrans-2,3-dihydrobenzofuran derivativesviaintramolecular Michael addition has been developed using a bifunctional tertiary amine–thiourea catalyst.