Short-term effect of IPED regimen in treatment of refractory Non-Hodgkun's lymphoma

Objective To observe the effect and toxicity of IPED regimen in treatment of refractory Non-Hodgkin's Lymphoma.Methods All 21 patients were treated over two cycles with IPED regimen. The IPED regimen was repeated every 28 days. The therapeutic effect was observed after treatment.Results 5 patients achieved complete remission(CR) ,10 partial remission(PR) 3 stable disease(SD),3 progression disease(PD). The overall response rate was 71.4%.The main side effects were myelosuppression and gastrointestinal reaction.Conclusion The IPED regimen is effective in the treatment of refractory Non-Hodgkin's lymphoma and it's toxicity is tolerable.