The induction of aryl hydrocarbon hydroxylase(AHH) of carp liver microsome by five aromatic hydrocarbon compounds

The aryl hydrocarbon hydroxylase(AHH) activity of carp liver microsome induced by five polyaromatic hydrocarbon (PAH) compounds was examined Five tested PAH named as phenanthrene; 9,10 phenananthrenquinone, pyrene, benzo[a]pyrene, 1 hydroxypyrene induced AHH activity to different extent There existed a good dose effect correlation between the AHH induction and aromatic hydrocarbons concentration The AHH activity of fish liver microsome can be used as a biomarker to evaluate the aromatic hydrocarbon contamination in waters The intense of AHH activity induced by five aromatic hydrocarbons which was related to the toxicity chemicals was as following: 1 hydroxypyrene benzo[a]pyrene; 9,10 phenananthrenquinone pyrene phenanthrene