Mechanical thrombectomy in patients with stroke due to large vessel occlusion in the anterior circulation and low scale score

医学 改良兰金量表 冲程(发动机) 闭塞 无症状的 大脑中动脉 外科 内科学 缺血性中风 缺血 机械工程 工程类
作者
Andrea Alexandre,Iacopo Valente,Giovanni Frisullo,Roberta Morosetti,Danilo Genovese,Andrea Bartolo,Riccardo Gigli,Claudia Rollo,Luca Scarcia,Francesca Carosi,Giusy Fortunato,Francesco D’Argento,Paolo Calabresi,Giacomo Della Marca,Alessandro Pedicelli,Aldobrando Broccolini
出处
期刊:Journal of Integrative Neuroscience [IMR Press]
卷期号:20 (3): 645-645 被引量:2
标识
DOI:10.31083/j.jin2003068
摘要

We sought to verify the benefit of mechanical thrombectomy in patients with acute ischemic stroke due to large vessel occlusion in the anterior circulation and low National Institute of Health stroke scale score at presentation. The prospective database of our stroke center was screened for patients with acute ischemic stroke due to large vessel occlusion and a baseline National Institute of Health stroke scale score ≤5 that had undergone mechanical thrombectomy. Outcome measures were the modified Rankin Scale (mRS) score at 90 days, brain bleeding events and death at 90 days. Out of 459 patients, 17 (12 females, mean age 70 ± 14 years) with occlusion of M1 or M2 segment of middle cerebral artery and baseline National Institute of Health stroke scale score ≤5 underwent mechanical thrombectomy. Eight patients (47%) were treated within 6 hours from the onset, 5 (29%) were treated beyond 6 hours, and 4 (24%) were wake-up strokes. Effective mechanical thrombectomy was achieved in 16 patients (94%) and associated with excellent functional outcomes at 3 months (mRS 0-1) in 13 (76%). The asymptomatic brain-bleeding event was observed in one patient 4 days after effective mechanical thrombectomy concerning safety issues. One patient died 1 month after mechanical thrombectomy of a cause unrelated to stroke. Our findings favor a potential benefit of mechanical thrombectomy in patients with stroke due to large vessel occlusion and low National Institute of Health stroke scale score at presentation. These patients may also benefit from a prolonged time window for treatment.
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