化学
表面改性
选择性
烷烃
双环分子
脂肪族化合物
药物化学
有机化学
碳氢化合物
催化作用
物理化学
作者
Takahide Fukuyama,Keiichi Yamada,Takeshi Nishikawa,Davide Ravelli,Maurizio Fagnoni,I. Ryu
出处
期刊:Chemistry Letters
[The Chemical Society of Japan]
日期:2018-02-05
卷期号:47 (2): 207-209
被引量:30
摘要
Site-selectivity in C(sp3)–H functionalization of aliphatic alcohols and alkanes was studied using the decatungstate anion as a photocatalyst. In the case of aliphatic alcohols, C–H bond α to the hydroxy group was preferentially functionalized. The α-site-selectivity is rationalized by polar effects imparted by the hydroxy group in the SH2 transition states. In contrast, C–H functionalization of alkanes was largely affected by steric effects.
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