The influences of two kinds of indicators of potassium persulfate and ammonium persulfate-sodium bisulfate on the graft polymerization of acrylic acid onto cassava starch were studied. The reaction conditions of graft polymerization, such as concentration of indicator, reaction temperature, concentration and degree of neutralization of monomer and reaction time,were investigated by the single factor experiment. By aimed the three factors of the grafted ratio, the monomer conversion ratio and the graft efficiency, the best conditions of reaction was found: used ammonium persulfate-sodium bisulfateas indicator, the concentration of acrylic acid was 1.1 mol/L, the temperature was 35℃,the concentration of the initiator was 2.8 mmol/L, the time was 3h,the neutral degree was 80%.