According to the application requirement of grain storage environment, a monitoring system is designed, which consists of the PC monitoring center and ZigBee wireless sensor network. A node development strategy with the core of CC2530 chip and CC2591 chip was adopt, and according to Z-Stack, the software ZigBee networking system is designed. The PC monitoring interface is designed based on VC6.0 platform. Experimental results show that the data collection is accurate and data transmission is good in real-time.