Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk
医学
环境卫生
作者
Sandro Marini,Tamara N. Kimball,Ernst Mayerhofer,Reinier Tack,Jasper Senff,Savvina Prapiadou,Cyprien Rivier,Jonathan Duskin,Christina Kourkoulis,Guido J. Falcone,Nirupama Yechoor,Rudolph E. Tanzi,Jonathan Rosand,Sanjula Singh,Livia Parodi,Christopher D. Anderson
出处
期刊：Neurology [Lippincott Williams & Wilkins] 日期：2024-11-06卷期号：103 (10): e210014-e210014被引量：5
Across different genetic predispositions for stroke, LLD, and dementia, healthier lifestyle behaviors are protective for brain health, demonstrating the nondeterminism of genetic risk. Furthermore, differences in BCS behave as aggregate risk estimators of all 3 outcomes. Further work is needed to prospectively investigate the utility and performance of the BCS as a targeted intervention in populations at elevated genetic risk of age-related brain disease.
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