REVIEW ARTICLE ON HYPERURICAEMIA WITH AN APPROACH TO VATASHONITAM

Hyperuricaemia is the condition in which Serum uric acid level is elevated in blood above 7mg/dl for men and above 6mg/dl for women. Uric acid is formed when the body breaks down a chemical called Purines. The most amount of Uric acid dissolves in the blood, passes through the kidneys, and leaves the body. Uric acid is the final oxidation product of Purine degradation. Approximately 70% of the uric acid excreted by humans comes from endogenous production and food consumption, and the remaining 20% being primarily eliminated by the intestine. The elevated Serum uric acid level is because of either increased production, or decreased excretion of uric acid, or as a combination of both processes. Urate production is accelerated by Purine rich diet, Endogenous purine production, and error in Purine metabolism.