医学
粘膜皮肤区
鹦鹉热衣原体
皮肤病科
强力霉素
结膜
眼睑炎
角膜结膜炎
衣原体
免疫学
病理
抗生素
微生物学
疾病
生物
作者
Radhika S Gholap,Alexander Engelmann,Wuqaas M. Munir
出处
期刊:Eye & Contact Lens-science and Clinical Practice
[Ovid Technologies (Wolters Kluwer)]
日期:2023-09-20
卷期号:49 (12): 572-574
标识
DOI:10.1097/icl.0000000000001042
摘要
Introduction: This report highlights a postinfectious mucocutaneous inflammatory response involving the ocular surface and adnexa after Chlamydophila psittaci exposure. Case Description: A 35-year-old man presented after a prodrome of upper respiratory symptoms with rash and mucocutaneous blistering involving the ocular and oral mucosa, causing pseudomembranous conjunctivitis and corneal epithelial defects. Extensive inflammatory and infectious workup suggested recent C. psittaci infection. The patient was treated with doxycycline and supportive therapy, whereas the ocular surface was treated with lubrication and prophylactic antibiotics. In follow-up, he has retained excellent visual acuity but required scleral contact lenses to control ocular surface symptoms because of fibrotic changes of the marginal conjunctiva. Discussion: Such blistering inflammation has most commonly been described after pediatric respiratory infections because of Mycoplasma pneumoniae with additional instances related to Chlamydia pneumoniae , Epstein–Barr virus, influenza B, and other stimuli . To the best of our knowledge, this is the first reported case of C. psittaci– induced reactive infectious mucocutaneous eruption (RIME). RIME is a rare parainfectious inflammatory condition with sequelae frequently involving the periocular mucosa. Although systemic and nonocular adverse outcomes in this condition tend to be self-limited, the impact on the ocular surface may be severe, and the consequences to vision may be ongoing, especially if not treated aggressively at the outset.
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