Cell Differentiation of DPSCs Infected With Different Periodontal Pathogens

DPSCs showed the homogeneity and heterogeneity when infected by these two pathogens. DPSCs differentiated into smooth muscle-related cells and mineralization-related cells when infected by C. periodontitidis and P. gingivalis, respectively. Our results will facilitate understanding and therapeutic strategies of primary periodontal disease with secondary endodontic involvement.