The characteristics of menopause symptoms exhibit considerable variation across different countries and regions. Understanding these variations is crucial for developing strategies to manage the menopausal symptoms specific to each region. A comparative analysis of menopausal symptoms between the East and the West is presented, based on a review of the epidemiological literature and data. In the East, the age of menopause and the onset of the menopausal symptoms were observed to occur slightly earlier than in the West. The two most commonly reported menopausal symptoms in western countries are hot flushes and sleeplessness, whereas Asian women mostly report somatic symptoms. The reported prevalence of menopausal symptoms varies considerably and differs substantially between the studies. These variations may be related to research methods, sample size, ethnicity, culture, socioeconomic differences, menopausal status and other factors.