The emerging hydrogels for fruit preservation have aroused widespread scientific interest. However, it is challenging for current hydrogel packaging to incorporate the required multifunctional properties. Herein, a gelatin-based (Gel/G) hydrogel film is elaborately designed as an efficient mango packaging and preservation system. Multiple dynamic non-covalent interactions serve as sacrificial bonds to dissipate energy and endow the hydrogel with remarkable elongation (up to 1204%) and tensile strength (216.08 kPa). The optimized Gel/G hydrogel also provides excellent transparency, UV blocking, degradability, water vapor barrier, biosafety and anti-drying performance. Notably, compared with the blank control and commercial PE film, the Gel/G hydrogel-packed mangoes maintain the color and smoothness of epidermis, and delay the browning and softening processes of fruits. Additionally, the pH value, TSS, and MDA contents of Gel/G hydrogel-packed mangoes remain at a lower level and vary stably, and TA consumption is less. These results suggest that the Gel/G hydrogel packaging has a remarkable effect on mango preservation and can effectively delay its ripening and senescence process. Therefore, our work contributes to the in-depth understanding and rational design of food packaging and multifunctional hydrogel preservation films. • gelatin/P(AA-Am) hydrogel was prepared by UV radiation for mango preservation. • The hydrogel exhibited excellent elongation (1204%) and anti-drying performance. • Degradability, UV blocking, transparency and biosafety were combined in a hydrogel. • Gel/G hydrogel delayed the dehydration, browning and softening process of mango. • Gel/G hydrogel reduced nutrient consumption and MDA production of mango.