Research Progress on Direct Trifluoromethylselenylation

The trifluoromethylselenylation reaction is another important research topic after trifluoromethylsulfanylation reaction in recent years.Because the trifluoromethylselenyl group contains two important chemical elements, fluorine and selenium, and the compounds containing trifluoromethyl selenide have important potential biological activities, more and more researchers begin to turn their attention to this new group in recent years.In this paper, according to the three reaction types of nucleophilic trifluoromethylselenylation reaction, electrophilic trifluoromethylselenylation reaction and radical trifluoromethylselenylation reaction, the research results of domestic and foreign scholars on direct trifluoromethylselenylation reaction in recent 6 years are comprehensively summarized, and some reaction mechanisms are discussed in detail.Finally, the direct trifluoromethylselenylation reaction is summarized and prospected.