汗水
汗腺
无汗
多汗症
表型
遗传力
生物
温度调节
内科学
医学
内分泌学
基因
遗传学
皮肤病科
作者
Wenyan Chen,Jinxi Li,Kaimei Xu,Junyu Luo,Mengran Wang,Yu Liu,Fudi Wang,Siyuan Du,Wenjie Xu,Jing Ge,y. li,Bingfei Fu,Jingze Tan,Ying Yang,Jiucun Wang,Xiangyang Xue,Li Jin,Zhaohui Yang,Fan Liu,Sijia Wang
标识
DOI:10.1016/j.jid.2024.02.037
摘要
Sweat glands are widely distributed across human skin, playing an essential role in thermoregulation and body temperature maintenance, while sweat gland dysfunction is associated with various skin disorders, such as hyperhidrosis and anhidrosis (Asahina et al., 2015). Sweat gland density (SGD) varies significantly between and within ethnic groups (Lee et al., 2010). Despite the estimated heritability of SGD up to 0.66 (Scobbie and Sofaer, 1987), the underlying genetic factors and mechanisms responsible for this variation remain largely unexplored.
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