Role of secretory IgA in the pathogenesis of IgA nephropathy

Immuno globulin A nephropathy is the most common primary glomerular disease in China.IgA nephropathy occurs frequently after respiratory or digestive tract infections.some scholars speculate that mucosal immunity is related to IgA nephropathy. Secretory IgA plays an important role in IgA nephropathy. This article reviews the progress of secretory IgA in the pathogenesis of Secretory IgA nephropathy. Key words: Secretory immuno globlin A; Mucosal immune; immuno globlin A nephropathy; Complement; Mesangial cell