拉伤
病毒株
人口
病毒学
病毒
流行病模型
生物
理论(学习稳定性)
基本再生数
医学
计算机科学
环境卫生
解剖
机器学习
作者
Miguel Fudolig,Réka Howard
标识
DOI:10.1101/2020.03.19.20039198
摘要
Abstract We study a novel multi-strain SIR epidemic model with selective immunity by vaccination. A newer strain is made to emerge in the population when a preexisting strain has reached equilbrium. We assume that this newer strain does not exhibit cross-immunity with the original strain, hence those who are vaccinated and recovered from the original strain become susceptible to the newer strain. Recent events involving the COVID-19 virus demonstrates that it is possible for a viral strain to emerge from a population at a time when the influenza virus, a well-known virus with a vaccine readily available for some of its strains, is active in a population. We solved for four different equilibrium points and investigated the conditions for existence and local stability. The reproduction number was also determined for the epidemiological model and found to be consistent with the local stability condition for the disease-free equilibrium.
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