Choreatic Symptoms During and After Treatment with Paliperidone and Escitalopram

Paliperidone, the first orally applicable atypical neuroleptic marketed as an extended-release preparation, is generally well tolerated [ 1 ] [ 5 ]. Over the last weeks, we have observed several young patients with schizophrenia, who showed significant akathisia during paliperidone treatment. Here we report the case of a depressed and psychotic patient who developed a dramatic choreatic syndrome during treatment with escitalopram and paliperidone.