KBr-enabled electrochemical transformation of alkynes into α-bromoketones/1,2-diketones

In recognition of the crucial role of ketone motifs in significant organic transformations and the synthesis of valuable molecules (e.g., pharmaceuticals, pesticides, and fine chemicals), we herein report an electrochemical protocol for the synthesis of α-bromoketones and 1,2-diketones from alkynes. This method employs safe and cost-effective KBr as both the bromine source and supporting electrolyte, while NFSI acts as an electron acceptor and MeOH serves as the solvent. The transformation proceeds smoothly, delivering the desired products in good yields.