HSP27:mechanisms of cellular protection against artery injury

Heat shock protein 27 (HSP27) is an important member of small molecular weight heat shock protein family,upregulation when the body under stress,can protect cell function via the effect of molecular chaperone,regulating cell movement,anti apoptosis,anti-oxidative stress and anti-inflammatory.HSP27 is a recently reported potential biomarker of atherosclerosis.The serum HSP27 levels were inversely related to atherosclerotic burden.HSP27 may be a significant new therapeutic target in Atherosclerosis.