Modified aluminonickel molibdenum catalysts are studied in hydropurification and hydroisomerisation process of gasoline and diesel oil fractions. Catalysts were tested on flow reactor at the temperature 593–673 K, pressure 2.0-4.5 MPa, 2-7 hours-1 feed velocity. It was shown that synthesized catalysts have polyfunctional properties and they allow to obtain low sulfureous gasoline and diesel fuel with improved characteristics.