Recent advances in bioreactor and its engineering

The engineering methodologies and key technologies for the bioreactor design and the scale-up were discussed.The development trends in bioreactors for the production of biotechnology products were described,including a bioreactor system focusing on metabolic flux detection and analysis,the improved stirred-tank bioreactor based on computational fluid dynamics,microbioreactor,bioreactor for mammalian cell,and enzymatic bioreactor.