NEPHROTOXICITY: AN OVERVIEW

Nephrotoxicity is one of the most common situations faced by people due to easy availability of over the counter medication like NSAIDs, antibiotics and angiotensin converting enzyme inhibitors etc. There are various types of nephrotoxicities caused by various drugs like aminoglycosides nephrotoxicity, amphotericin B nephrotoxicity, cisplatin nephrotoxicity and herbal nephrotoxicity etc. So, experiments to discover nephroprotective agents are going on worldwide employing various animal models. Every year so many herbal drugs are experimentally proved to be possed nephroprotective activity. This present review is aimed to enlist various animal models employed in searching nephroprotective agents and some of the medicinal plants, which are scientifically proven in treating harmful effects of nephrotoxicity. Keywords: Nephrotoxicity, Nephroprotective activity, Medicinal plants