阿法替尼
医学
培美曲塞
内科学
表皮生长因子受体
肿瘤科
腺癌
肺癌
化疗
临床研究阶段
危险系数
临床终点
吉非替尼
胃肠病学
顺铂
癌症
临床试验
置信区间
作者
Lecia V. Sequist,James Chih‐Hsin Yang,Nobuyuki Yamamoto,Kenneth J. O’Byrne,Vera Hirsh,Tony Mok,Sarayut Lucien Geater,Sergey Orlov,Chun‐Ming Tsai,Michael Boyer,Wu‐Chou Su,Jaafar Bennouna,Terufumi Kato,В. А. Горбунова,Ki Hyeong Lee,Riyaz Shah,Dan Massey,Victoria Zazulina,Mehdi Shahidi,Martin Schüler
摘要
The LUX-Lung 3 study investigated the efficacy of chemotherapy compared with afatinib, a selective, orally bioavailable ErbB family blocker that irreversibly blocks signaling from epidermal growth factor receptor (EGFR/ErbB1), human epidermal growth factor receptor 2 (HER2/ErbB2), and ErbB4 and has wide-spectrum preclinical activity against
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