生物
骨髓生成
U937电池
细胞培养
血液学
免疫学
效应器
癌症研究
细胞生物学
造血
遗传学
干细胞
作者
Paul E. Harris,Peter Ralph
摘要
The human leukemic myeloblast HL-60 and monoblast U937 cell lines have made important contributions to the disciplines of cancer, hematology, and immunology. As sources of leukemic cells, they have been used for the study of neoplasia and therapeutics. As sources of hemic cells, they have been used for biochemical and biological analysis of regulation and differentiation in myelopoiesis. When stimulated with immunomodulatory factors, the cell lines develop properties of host-defense effector cells. They are also a source of cytokines that affect other cell types.
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