Challenge of Giant Pituitary Tumors

he definition of giant pituitary tumors is unclear. Although some authors label giant tumors as those that are more T than 3 cm in their vertical height, others label those tumors as giant that are more than 4 cm. With respect to surgical treatment, tumors more than 4 cm in height are much more difficult to resect than those lesser than 4 cm (3, 4). The authors of this manuscript mention that they have treated tumors measuring 4e7 cm in size but, unfortunately, have shown by example tumors that are relatively small. The authors could have shown their best and largest tumor cases and those that were real giant pituitary tumors that they treated successfully. Surgery on giant pituitary tumors more than 4 cm in their vertical height has specific issues that are different from those in smaller tumors.