A new species of Physalis (Solanaceae, Solanoideae) endemic to northern Argentina is described as Physalis victoriana. It is an annual herb, with simple and antrorse trichomes, leaves obtuse at base, with undulate and sparsely toothed margins, yellow corolla without macules, and dark green to dark brown berries. Description, illustrations, field pictures, and a distribution map of the new species are included.