斯特罗普效应
电休克疗法
记忆广度
磁刺激
韦氏成人智力量表
神经认知
心理学
听力学
认知
试制试验
临床心理学
精神科
物理医学与康复
医学
神经心理学
工作记忆
刺激
神经科学
作者
Ahmed Abdel Latif,Mohamed Nasreldin,Ann Abdel Kader,Heba Fathy,Suaad Moussa,Mye A. Basheer,Adly Elsheikh,Nagwan Madbouly
出处
期刊:Journal of Psychiatric Practice
[Ovid Technologies (Wolters Kluwer)]
日期:2020-01-01
卷期号:26 (1): 23-36
被引量:9
标识
DOI:10.1097/pra.0000000000000436
摘要
Background: Studies have compared electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS) with regard to their clinical efficacy in the treatment of depression, but only a few studies have addressed their differential impact on cognition. The purpose of this study was to compare the neurocognitive side effects of both treatment modalities. Methods: In this comparative study, 40 patients with major depressive disorder referred for ECT were randomly assigned either to a course of 25 sessions of rTMS to the left dorsolateral prefrontal cortex or to a course of ECT ranging from 4 to 8 sessions. The primary outcome measures were the results of a cognitive battery that assessed different aspects of cognitive functioning. The cognitive battery comprised the Digit Span Subtest from the Wechsler Adult Intelligence Scale, the Stroop Color-Word Test-Victoria version, the Color Trails Test Trials 1 and 2, and the Rey-Osterrieth Complex Figure Test. Results: At the end of treatment, scores on the Digit Span Subtest, the Stroop Color-Word Test-Victoria version, and the Color Trails Test showed statistically significant better results in the rTMS group compared with the ECT group. Conclusions: rTMS was well tolerated with less negative impact on cognitive functioning than ECT.
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