材料科学
核梭杆菌
牙龈卟啉单胞菌
生物相容性
牙种植体
涂层
偷看
变形链球菌
复合材料
牙科
植入
粘附
细菌
医学
纳米技术
生物
冶金
聚合物
外科
牙周炎
遗传学
作者
Cui Guo,Ran Lu,Xin Wang,Chen Su
标识
DOI:10.1007/s13233-021-9042-3
摘要
Polyetheretherketone (PEEK) implant abutments are widely used in implant dentistry; however, they do not protect the implant against infections. We demonstrated that graphene oxide (GO) coating enhances the integration between implant surfaces and gingival tissues, which is crucial for peri-implant health. The GO coating was tightly fixed onto the PEEK surface by doping with dopamine which is self-polymerized into poly-dopamine (PDA). The in vitro study included antimicrobial and cellular tests. It revealed the inhibition of bacteria like Porphyromonas gingivalis (P. gingivalis), Fusobacterium nucleatum (F. nucleatum), and Streptococcus mutans (S. mutans). Moreover, it exhibited good adhesion and proliferation of human gingival fibroblasts (HGFs). Our results revealed that the PEEK-PDA-GO coating resisted bacteria and protected soft tissues against peri-implant complications.
科研通智能强力驱动
Strongly Powered by AbleSci AI