痴呆
精神病
路易氏体型失智症
抗精神病药
中止
临床全球印象
血管性痴呆
心理学
精神科
安慰剂
内科学
医学
疾病
精神分裂症(面向对象编程)
病理
替代医学
作者
Pierre N. Tariot,Jeffrey L. Cummings,Maria Soto‐Martin,Clive Ballard,Deniz Erten‐Lyons,David L. Sultzer,Davangere P. Devanand,Daniel Weintraub,Bradley McEvoy,James M. Youakim,Srdjan Stankovic,Erin P. Foff
标识
DOI:10.1056/nejmoa2034634
摘要
In a trial that was stopped early for efficacy, patients with dementia-related psychosis who had a response to pimavanserin had a lower risk of relapse with continuation of the drug than with discontinuation. Longer and larger trials are required to determine the effects of pimavanserin in dementia-related psychosis. (Funded by Acadia Pharmaceuticals; HARMONY ClinicalTrials.gov number, NCT03325556.).
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