变性人
排斥
心理学
扣带回前部
功能磁共振成像
社会心理的
精神病理学
临床心理学
感觉
前额叶皮质
发展心理学
额下回
精神科
神经科学
社会心理学
认知
精神分析
作者
Sven C. Mueller,Katrien Wierckx,Sara Boccadoro,Guy T’Sjoen
标识
DOI:10.1017/s0033291717003828
摘要
Abstract Background Stigmatization in society carries a high risk for development of psychopathology. Transgender persons are at particularly high risk for such stigmatization and social rejection by others. However, the neural correlates of ostracism in this group have not been captured. Method Twenty transgender men (TM, female-to-male) and 19 transgender women (TW, male-to-female) already living in their gender identity and 20 cisgender men (CM) and 20 cisgender women (CW) completed a cyberball task assessing both exclusion and re-inclusion during functional magnetic resonance imaging (fMRI). Results During psychosocial stress between-group differences were found in the dorsal and ventral anterior cingulate cortex (ACC) and the inferior frontal gyrus (IFG). Patterns were consistent with sex assigned at birth, i.e. CW showed greater activation in dorsal ACC and IFG relative to CM and TW. During re-inclusion, transgender persons showed greater ventral ACC activity relative to CW, possibly indicating persistent feelings of exclusion. Functional connectivity analyses supported these findings but showed a particularly altered functional connectivity between ACC and lateral prefrontal cortex in TM, which may suggest reduced emotional regulation to the ostracism experience in this group. Depressive symptoms or hormonal levels were not associated with these findings. Conclusion The results bear implications for the role of social exclusion in development of mental health problems in socially marginalized groups.
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