免疫抑制
医学
重症监护医学
恶性肿瘤
肺移植
移植
免疫系统
免疫学
外科
内科学
作者
Caroline Patterson,Elaine C. Jolly,Fay Burrows,N.J. Ronan,Haifa Lyster
标识
DOI:10.1016/j.ccm.2022.10.009
摘要
Most therapeutic advances in immunosuppression have occurred over the past few decades. Although modern strategies have been effective in reducing acute cellular rejection , excess immunosuppression comes at the price of toxicity, opportunistic infection , and malignancy . As our understanding of the immune system and allograft rejection becomes more nuanced, there is an opportunity to evolve immunosuppression protocols to optimize longer term outcomes while mitigating the deleterious effects of traditional protocols.
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