Florisil as an efficient reagent for deprotection of tert-butyl carbamates, carbonates and esters

Florisil (magnesium polysilicate) is an efficient and eco-friendly reagent for the deprotection of tert-butyl carbamates, carbonates, and ethers. Moderate to excellent yields could be achieved in the presence of other acid-sensitive groups. The separation of products is easy, and Florisil can be recycled several times without observing a decrease in yields.